Current Investigator-led Research

Global Coagulation Assays in Patients with High-Risk Cardiovascular Risk Factors
Principal investigator: Dr Yin Lim
Associate investigators: Dr Prahlad Ho, Dr David Barit, Dr Suresh Varadarajan, Dr Carol Chong
Status: Active – currently recruiting

Prospective Serial Evaluation of New Biomarkers of Thrombosis in Patients with Newly Diagnosed Venous Thromboembolism
Medical student: Oranut Aswapanyawongse
Principal Investigator: Dr Yin Lim, Dr Prahlad Ho
Status: Currently recruiting

Evaluation of New Biomarkers of Thrombosis in a Normal Population As Well As Anticoagulated and Hypercoagulable States
Principal Investigator: Dr Prahlad Ho, Dr Yin Lim
Status: Currently Recruiting

Use of Novel Oral Anticoagulants – Retrospective Review
Principal Investigator: Dr Rowena Brook
Supervisors: Dr Yin Lim, Dr Prahlad Ho
Status: Current

Global Coagulation Assays in Cancer Patients
Medical student: Brintha Krishnamoorthi
Supervisors: Dr Teresa Leung, Dr Rachel Cooke
Co-Investigators: Dr Yin Lim, Dr Prahlad Ho
Status: Current

Global Coagulation Assays in Obstetrics and Neonates
Medical student: Johnathan Tham
Supervisors: A/Prof Lisa Hui
Co-investigators: Dr Vanessa Manitta, Dr Prahlad Ho, Dr Yin Lim
Status: Current

Thrombophlebitis Post Varicose Vein Surgery
Principal Investigator: Dr Frank Hong
Co-Investigators: Dr Yin Lim, Dr Prahlad Ho, Mr Iman Bayat
Status: Current

Publications & Presentations

Publications

  • HY Lim, CC Chua, M Sleeman, M Tacey, G Donnan, H Nandurkar, P Ho. Venous thromboembolism management in Northeast Melbourne – How does it compare to international guidelines and data? Intern Med J 2017;47:1034-42.
  • CC Chua*, HY Lim*, M Tacey, H Nandurkar, P Ho. Retrospective evaluation of venous thromboembolism: Are all transient provoking events the same? Eur J Haem 2017;99:18-26. (* joint first authors)
  • P Ho, HY Lim, CC Chua, M Sleeman, M Tacey, G Donnan, H Nandurkar. Retrospective review of isolated distal deep vein thrombosis (IDDVT) – A benign entity or not? J Thromb Res 2016;142: 11-16
  • HY Lim, C Ng, G Donnan, H Nandurkar, P Ho Te n Years of Cerebral Venous Thrombosis: Male Gender and Myeloproliferative Neoplasm is Associated with Thrombotic Recurrence in Unprovoked Events. J Thrombosis and Thrombolysis 2016; doi 10.1007/s11239-016-1362-3
  • HY Lim, P Ho. Review: Direct Oral Anticoagulants in Dental Patients Including the Frail Elderly Population. Dentistry Journal 2016,4,7: doi:10.3390/dj4010007
  • La Brooy B, Ho P, Lim KW. Letter to the Editor: NOAC in the elderly – What is the evidence? Int Med J 2015;45(6):685-6
  • La Brooy B, Ho P. New oral anticoagulants: An approach to the elderly. J Pharm Pract Research 2015;45:217-225
  • Ho P, La Brooy B, Hayes L, Lim KW. Review Article: Direct oral anticoagulants (DOACs) in the frail elderly: A geriatric perspective. Sem Throm Haem 2015 (in press)
  • La Brooy B, Ho PW, Lim KW. A case of reversible cognitive impairment associated with the use of Dabigatran. J Am Geriatr Soc 2015 Aug;63(8):1717-9
  • Ho P, Khan S, Hayes L. Case Report: Extensive cerebral venous sinus thrombosis after Romiplostim treatment for immune thrombocytopenia (ITP) despite severe thrombocytopenia. Int Med J 2014

2017 Presentations

  • Leung P, Manitta V, Nandurkar H, Lim HY, Ho P. Evaluation of global coagulation assay parameters in normal and thrombocytopenic populations. HAA Annual Scientific Meeting – Sydney (poster presentation with mini-oral – winner of best Clinical Poster Award)
  • Lim HY, Ng C, Rigano J, Nandurkar H, Ho P. Utility of global coagulation assays in myeloproliferative neoplasm. HAA Annual Scientific Meeting – Sydney (oral presentation)
  • Munnings M, Barit D, Nandurkar H, Lim HY, Ho P. Global coagulation assay changes in haemodialysis patients. HAA Annual Scientific Meeting – Sydney (oral presentation)
  • Brook R, Su Y, Kitipornchai T, Chellaram V, Ho P, Lim HY. Real-world experience of direct oral anticoagulants use in North Melbourne, Australia. HAA Annual Scientific Meeting – Sydney (oral presentation)
  • Brook R, Ho P, Lim HY. Direct oral anticoagulant use in patients with active malignancy: Evaluation of demographics and safety outcomes. HAA Annual Scientific Meeting – Sydney (poster presentation)
  • Munnings M, Varadarajan S, Barit D, Leung T, Nandurkar H, Ho P. Lim HY. Evaluation of global coagulation assays in patients with risk factors for cardiovascular disease. HAA Annual Scientific Meeting – Sydney (poster presentation)
  • Lim HY, Ng C, Rigano J, Nandurkar H, Ho P. Global coagulation assays in normal control: the impact of age, ethnicity and gender. HAA Annual Scientific Meeting – Sydney (poster presentation)
  • Lambros P, Savage S, Chellaram V, Ho P, Lim HY. Outpatient management of deep vein thrombosis using direct oral anticoagulants is safe and cost-effective. HAA Annual Scientific Meeting – Sydney (poster presentation)
  • Rigano J, Ng C, Nandurkar H, Lim HY, Ho P. P-selectin as a marker of cardiovascular risk in normal controls and myeloproliferative neoplasm. HAA Annual Scientific Meeting – Sydney (poster presentation)
  • Lim HY, Leung P, Manitta V, Nandurkar H, Ho P. Evaluation of global coagulation assays in normal and thrombocytopenic populations. American Society of Haematology – Atlanta (poster presentation)
  • Lim HY, Ng C, Rigano J, Tacey M, Nandurkar H, Ho P. Utility of global coagulation assays in myeloproliferative neoplasm. American Society of Haematology – Atlanta (poster presentation)

2016 Presentations

  • Ng C, Grigg A, Nandurkar H, Ho P. Evaluation of thromboelastography in patients with myeloproliferative neoplasm: Platelet count >600 is associated with prothrombotic parameters. International Poster –  ISTH Meeting Montpellier France
  • Rigano J, Ng C, Smith C, Ho P. New Oral Anticoagulant (NOAC) is associated with increased in-vitro anticoagulant effect variability as measured using Thrombin Generation. International Poster – ISTH Meeting Montpellier France
  • Stevens H, Leung T, Ho P. Increased Menstrual Bleeding seen with Rivaroxaban Use. Local Oral Presentation – HAA 2016 (Melbourne)
  • 2015 Presentations
  • Lim HY, Ng C, Donnan G, Nandurkar H, Ho P. Cerebral venous sinus thrombosis: 10 years experience in Northeast Melbourne. HAA 2015 Annual Scientific Meeting, Adelaide, Oct 2015.
  • Ng C, Grigg A, Nandurkar H, Ho P. Evaluation of thromboelastography in patients with myeloproliferative neoplasm: Platelet count >600 is associated with prothrombotic parameters. HAA 2015 Annual Scientific Meeting, Adelaide, Oct 2015.
  • Rigano J, Ng C, Smith C, Ho P. New Oral Anticoagulant (NOAC) is associated with increased in-vitro anticoagulant effect variability as measured using Thrombin Generation. HAA 2015 Annual Scientific Meeting, Adelaide, Oct 2015.
  • Chua C, Lim HY, Sleeman M, Ho P. Provoked venous thromboembolism in non-cancer patients: are they the same? HAA 2015 Annual Scientific Meeting, Adelaide, Oct 2015.
  • Lim HY, Chua C, Sleeman M, Hayes L, Smith C, Ho P. Venous thromboembolism in Northeast Melbourne, Australia: Evaluation of epidemiology, risk factors and treatment strategies in the warfarin era. 2015 International Society of Thrombosis & Haemostasis (ISTH) Congress, Toronto, June 2015.
  • Lim HY, Chua C, Sleeman M, Hayes L, Smith C, Ho P. Below knee deep vein thrombosis: a benign entity or not? 2015 International Society of Thrombosis & Haemostasis (ISTH) Congress, Toronto, June 2015. (Top 20% of all presentations)
  • Lim HY, Chua C, Sleeman M, Ho P. Venous thromboembolism in Northeast Melbourne, Australia: Evaluation of epidemiology, risk factors and treatment strategies in the warfarin era. 20th congress of European Haematology Association, Vienna, June 2015.
  • Chua C, Lim HY, Sleeman M, Ho P. Provoked venous thromboembolism in non-cancer patients: are they the same? 20th congress of European Haematology Association, Vienna, June 2015.
  • Lim HY, Ng C, Rigano J, Smith C, Nandurkar H, Ho P. Influence of ethnicity on global coagulation assays – thromboelastography (TEG) and calibrated automated thrombography (CAT). HAA 2015 Annual Scientific Meeting, Adelaide, Oct 2015.
  • Chellaram V, Hayes L, Ho P. NOAC Guidance System. International Forum on Quality and Safety in Health Care, London 2015.